LIPOSOMAL GEL OF DICLOFENAC SODIUM AS TOPICAL DELIVERY SYSTEM
نویسندگان
چکیده
منابع مشابه
Design and Evaluation of Ocular Controlled Delivery System for Diclofenac Sodium
Diclofenac sodium as ophthalmic dosage form is used in patients treatment of eye pain, swelling and redness recovering from cataract surgery but it faces the bioavailability limitation of eye drops due to effective protective mechanisms and corneal barrier functions in the eyes. Therefore, this investigation was aimed to develop ocular film formulations to achieve controlled drug release. Drug ...
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The purpose of this study was to investigate microemulsions as delivery systems for diclofenac sodium (DS). Microemulsion systems were composed of: soybean oil, nonionic surfactants (Brij 58 and Span 80), and different alcohols: ethanol, and 1-buthanol as cosurfactant. The optimum surfactant: cosurfactant (S:CoS) weight ratios and microemulsion areas were detected by the aid of ternary phase di...
متن کاملDesign and Evaluation of Diclofenac Sodium Megaloporous Matrix System Aimed for Colonic Drug Delivery
Megaloporous controlled release tablets of diclofenac sodium (DS) were prepared with two kinds of granules. One of them is the restraining-phase matrix granule (RMG) and it controls the release rate of the drug. The other one is the soluble housing-phase matrix granule (HMG) and controls liquid penetration into the system. Carnauba wax and Eudragit L 100 polymers were used to constitute th...
متن کاملDesign and Evaluation of Ocular Controlled Delivery System for Diclofenac Sodium
Diclofenac sodium as ophthalmic dosage form is used in patients treatment of eye pain, swelling and redness recovering from cataract surgery but it faces the bioavailability limitation of eye drops due to effective protective mechanisms and corneal barrier functions in the eyes. Therefore, this investigation was aimed to develop ocular film formulations to achieve controlled drug release. Drug ...
متن کاملComparison of in vitro dialysis release methods of loperamide-encapsulated liposomal gel for topical drug delivery
BACKGROUND The purpose of this study was to determine the most appropriate dialysis equilibrium method to assess liposomal gel formulations containing hydrophobic drugs, to give the most accurate indication of drug release. METHODS Loperamide hydrochloride-encapsulated liposomes, composed of L-α-phosphatidylcholine and cholesterol (molar ratio of 2:1), were prepared according to the method of...
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ژورنال
عنوان ژورنال: Bulletin of Pharmaceutical Sciences. Assiut
سال: 2007
ISSN: 1110-0052
DOI: 10.21608/bfsa.2007.64181